Organ level therapeutic discovery
Discover unexpected organ level disease mechanisms and identify corresponding novel therapeutic modalities. Our current focus is on disease areas with organ level manifestation including fibrosis and skin disorders.
In vivo reprogramming therapies
Identify novel therapies by reprogramming specific cellular behaviour within an organ. This include changing disease cell identity to another cell type or to convert abnormal cell to a functional cell to restore the normal organ functions.
Cell behaviour engineering and conversion
Identify novel mechanisms and modalities to engineer and convert one cell type to another. This leads to optimal cell conversion protocols for cell manufacturing and disease modelling with application in cell therapy and drug discovery.